Aquaporin 4 抗体 (AA 254-323)
Quick Overview for Aquaporin 4 抗体 (AA 254-323) (ABIN7126588)
抗原
See all Aquaporin 4 (AQP4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 254-323
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特异性
- In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Human recombinant AQP4 protein fragment (around aa254-323) (exact sequence is proprietary)
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亚型
- IgG1
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anti-Aquaporin 4 (AQP4) (AA 271-323) antibody
AQP4 适用: 人, 小鼠, 大鼠 WB, ICC, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 178-317) antibodyAQP4 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Aquaporin 4 (AQP4) (AA 244-323) antibodyAQP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 295-323), (C-Term) antibodyAQP4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 253-323) antibodyAQP4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) antibodyMicroarray verified AQP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB430199 unconjugated
anti-Aquaporin 4 (AQP4) antibodyMicroarray verified AQP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB287702 unconjugated
anti-Aquaporin 4 (AQP4) antibodyAQP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 258-274) antibodyAQP4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 4 (AQP4) (AA 178-317) antibodyAQP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human skeletal muscle, small intestine or brain tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Aquaporin 4 (AQP4)
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别名
- AQP4
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背景
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WCH4, Mercurial-insensitive water channel (MIWC), HMIWC2,Aquaporin 4 (AQP4)
Cellular localisation: Membrane. -
分子量
- 34kDa
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基因ID
- 361, 315369
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UniProt
- P55087
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途径
- Sensory Perception of Sound
抗原
-
