IL-15 抗体
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北京 101111
Quick Overview for IL-15 抗体 (ABIN7126581)
抗原
See all IL-15 (IL15) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the i² signaling subunit of the IL-2R. Evidence also suggests that like IL-2, IL-4 and IL-7, IL-15 utilizes the common IL-2Ri³ subunit.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human IL15(exact sequence is proprietary)
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亚型
- IgG1
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anti-Interleukin 15 (IL15) (AA 50-162) antibody
IL15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 48-162) antibodyIL15 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 1-162) antibodyIL15 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Interleukin 15 (IL15) (AA 46-162) antibodyIL15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Interleukin 15 (IL15) (AA 30-129) antibodyIL15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Interleukin 15 (IL15) antibodyIL15 适用: 人 WB, ELISA, IP, Func, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human placenta,skeletal muscle or adrenal gland.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- IL-15 (IL15) (Interleukin 15 (IL15))
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别名
- IL15
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背景
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Interleukin-15 (IL-15), MGC9721,Interleukin-15 (IL-15)
Cellular localisation: Secreted. Cytoplasm. Nuclear. -
分子量
- 14-15kDa
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基因ID
- 3600, 654378
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途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
抗原
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