IL-5 抗体
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北京 101111
Quick Overview for IL-5 抗体 (ABIN7126576)
抗原
See all IL-5 (IL5) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Interleukin-5, or IL-5, was originally discovered as a soluble T cell-derived factor, called T cell-replacing factor (TRF), that induced T cell-depleted activated B cells to secrete immunoglobulin. Native IL-5 is a disulfide-linked homodimer. IL-5 is initially synthesized as a precursor with a 19 amino acid signal peptide which is cleaved to form a 112 amino acid mature protein. Murine and human IL-5 exhibit 70 % sequence identity at the amino acid level. IL-5 exerts its biological activity through the IL-5 receptor (IL-5R), which is composed of at least two chains: an chain that binds IL-5 with low affinity and a chain that does not bind IL-5, but together with the IL-5 a chain, constitutes the high affinity IL-5 receptor. The chain is common to the IL-3, IL-5 and GM-CSF receptors and has been shown to signal through the JAK/Stat pathway.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human IL5 protein corresponding to the mature protein (exact sequence is proprietary)
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亚型
- IgG2b
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anti-Interleukin 5 (IL5) (AA 20-134) antibody
IL5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 5 (IL5) (AA 20-134) antibodyIL5 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 5 (IL5) (AA 21-70) antibodyIL5 适用: 人, 小鼠, 大鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 5 (IL5) (AA 56-132) antibodyIL5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 5 (IL5) (AA 20-134) antibodyIL5 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 5 (IL5) (AA 20-134) antibodyIL5 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Interleukin 5 (IL5) antibodyIL5 适用: 山羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 5 (IL5) antibodyIL5 适用: 人 ELISA, D, ELISA (Capture) 宿主: 大鼠 Monoclonal JES1-39D10 unconjugated
anti-Interleukin 5 (IL5) antibodyIL5 适用: 小鼠 ELISA 宿主: 大鼠 Monoclonal TRFK5 unconjugated
anti-Interleukin 5 (IL5) antibodyIL5 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human thymus or tonsil tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- IL-5 (IL5) (Interleukin 5 (IL5))
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别名
- IL5
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背景
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B-cell differentiation factor I, Colony stimulating factor, EDF, Eosinophil differentiation factor, Interleukin 5 (colony stimulating factor, eosinophil), T Cell Replacing Factor, TRF,Interleukin-5 (IL-5)
Cellular localisation: Secreted. Extracellular space. -
分子量
- 17kDa
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基因ID
- 3567, 2247
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途径
- JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
抗原
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