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IL3RA 抗体 (AA 26-171)

This 小鼠 单克隆 anti-IL3RA antibody specifically detects IL3RA in ELISA 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN7126575
发货至: 中国
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Quick Overview for IL3RA 抗体 (AA 26-171) (ABIN7126575)

抗原

See all IL3RA 抗体
IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL3RA antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)
  • 抗原表位

    • 32
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    • 2
    • 2
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    • 2
    • 2
    • 2
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    AA 26-171

    特异性

    CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human IL3RA protein fragment (around aa 26-171) (exact sequence is proprietary)

    亚型

    IgG2a
  • 应用备注

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Optimal dilution for a specific application should be determined.

    Positive_Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    别名

    IL3RA

    背景

    CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal,IL3RA / CD123 (Acute Myeloid Leukemia Marker)
    Cellular localisation: Cell surface and cytoplasm.

    分子量

    ~70kDa

    基因ID

    3563, 632790

    UniProt

    P26951

    途径

    JAK/STAT Signaling
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