IL-2 抗体 (AA 21-153)
Quick Overview for IL-2 抗体 (AA 21-153) (ABIN7126565)
抗原
See all IL-2 (IL2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 21-153
-
特异性
- Interleukin-2 (IL-2) is a T cell stimulatory cytokine that induces T cell proliferation and NK cell proliferation and activation. Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL-2 induces CTLA-4 and also functions as a survival factor for lymphocytes.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant fragment (around aa 21-153) of human IL2 protein (exact sequence is proprietary)
-
亚型
- IgG2a
-
-
-
-
应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human thymus or tonsil tissue.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- IL-2 (IL2) (Interleukin 2 (IL2))
-
别名
- IL2
-
背景
-
Aldesleukin, Involved in regulation of T cell clonal expansion, Lymphokine, POIL2, T-cell growth factor (TCGF),Interleukin-2 (IL-2)
Cellular localisation: Secreted. -
分子量
- 15kDa
-
基因ID
- 3558, 89679
-
途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
-