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APOE 抗体 (AA 19-119)

This anti-APOE antibody is a 小鼠 单克隆 antibody detecting APOE in IHC (f). Suitable for 人.
产品编号 ABIN7126547
发货至: 中国

Quick Overview for APOE 抗体 (AA 19-119) (ABIN7126547)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This APOE antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 19-119

    特异性

    In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human recombinant APOE protein fragment (around aa19-119) (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human liver, spleen or kidney tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    APOE

    背景

    AD2, Apo-E, Apolipoprotein E3, Apoprotein, LDLCQ5, LPG,Apolipoprotein E / APOE
    Cellular localisation: Secreted.

    分子量

    36kDa

    基因ID

    348, 654439

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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