ZNF81 抗体
Quick Overview for ZNF81 抗体 (ABIN7126545)
抗原
See all ZNF81 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNAbinding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF81, also known as HFZ20 or MRX45, is a transcriptional regulator belonging to the krueppel C2H2-type zincfinger protein family. It localizes to the nucleus and contains 12 C2H2-type zinc fingers and one KRAB domain. Mutations in the gene encoding ZNF81 are implicated in nonsyndromic X-linked mental retardation (XLMR).
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human ZNF81 protein
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亚型
- IgG2b
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Western Blot (1-2 μg/mL),Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ZNF81 (Zinc Finger Protein 81 (ZNF81))
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别名
- ZNF81
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背景
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HFZ20, Mental Retardation, X-linked 45 (MRX45),ZNF81 / Zinc finger protein 81 (Transcription Factor)
Cellular localisation: Nucleus. Cytoplasm (granular). -
分子量
- 75.9kDa
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基因ID
- 347344, 504609
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UniProt
- P51508
抗原
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