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Apolipoprotein D 抗体 (AA 21-119)

This anti-Apolipoprotein D antibody is a 小鼠 单克隆 antibody detecting Apolipoprotein D in IHC (f). Suitable for 人.
产品编号 ABIN7126542
发货至: 中国

Quick Overview for Apolipoprotein D 抗体 (AA 21-119) (ABIN7126542)

抗原

See all Apolipoprotein D (APOD) 抗体
Apolipoprotein D (APOD)

适用

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宿主

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小鼠

克隆类型

  • 48
  • 9
单克隆

标记

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This Apolipoprotein D antibody is un-conjugated

应用范围

  • 42
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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

    • 15
    • 7
    • 5
    • 3
    • 2
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    • 1
    • 1
    • 1
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    AA 21-119

    特异性

    Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human recombinant APOD protein fragment (around aa21-119) (exact sequence is proprietary)

    亚型

    IgG2
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human liver, kidney or spleen.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Apolipoprotein D (APOD)

    别名

    APOD

    背景

    APO-D protein,Apolipoprotein D / APO-D
    Cellular localisation: Secreted.

    分子量

    30kDa

    基因ID

    347, 522555

    UniProt

    P05090

    途径

    Platelet-derived growth Factor Receptor Signaling
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