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APOB 抗体 (AA 592-689)

This 小鼠 单克隆 antibody specifically detects APOB in IHC (f). It exhibits reactivity toward 人.
产品编号 ABIN7126529
发货至: 中国
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Quick Overview for APOB 抗体 (AA 592-689) (ABIN7126529)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

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宿主

  • 80
  • 45
  • 14
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  • 2
小鼠

克隆类型

  • 84
  • 58
单克隆

标记

  • 60
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  • 2
  • 2
  • 2
  • 1
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This APOB antibody is un-conjugated

应用范围

  • 86
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  • 9
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  • 2
  • 1
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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 592-689

    特异性

    Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein BmRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steadystate proportion of edited and unedited RNA molecules. Two forms of apoBare known to circulate in the plasma of mammals. ApoB-100 is a proteinprimarily synthesized in the liver as a structural component of very low densitylipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesizedin the small intestine and contains the amino-terminal 2,152 amino acids ofthe larger protein. This organ-specific partitioning of apoB production is theresultof RNA editing of a common apoB gene.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human recombinant APOB protein fragment (around aa592-689) (exact sequence is proprietary)

    亚型

    IgG2b
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human liver or kidney tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    APOB

    背景

    ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4,Apolipoprotein B /APOB
    Cellular localisation: Cytoplasm. Secreted.

    分子量

    512kDa

    基因ID

    338, 120759

    UniProt

    P04114

    途径

    Lipid Metabolism
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