HOXB2 抗体 (AA 114-220)
Quick Overview for HOXB2 抗体 (AA 114-220) (ABIN7126513)
抗原
See all HOXB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-220
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特异性
- Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (aa114-220) of human HOXB2
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亚型
- IgG2b
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anti-Homeobox B2 (HOXB2) (N-Term) antibody
HOXB2 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B2 (HOXB2) antibodyHOXB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B2 (HOXB2) (N-Term) antibodyHOXB2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B2 (HOXB2) (AA 71-120) antibodyHOXB2 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B2 (HOXB2) (AA 282-306), (C-Term) antibodyHOXB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, MCF-7 or Jurkat cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- HOXB2 (Homeobox B2 (HOXB2))
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别名
- HOXB2
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背景
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Homeo box 2H, homeo box B2, homeobox B2, Homeobox protein Hox-2.8, Homeobox protein Hox-2H, Homeobox protein Hox-B2, Hox 2 8, Hox 2H, HOX2, HOX2H, hoxb2, HXB2_HUMAN, K8, K8 home protein,HOXB2 (Transcription Factor)
Cellular localisation: Nucleus. Nucleoplasm. -
分子量
- 37.9kDa
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基因ID
- 3212, 514289
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UniProt
- P14652
抗原
-
