GTF2H2 抗体
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- 抗原 See all GTF2H2 抗体
- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GTF2H2 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and Mat1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
- 交叉反应 (详细)
- Human
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human GTF2H2 protein
- 亚型
- IgG1
- Top Product
- Discover our top product GTF2H2 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or MCF7 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
- 别名
- GTF2H2 (GTF2H2 产品)
- 背景
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Basic transcription factor 2 44 kDa subunit, BTF2, BTF2-p44, BTF2P44, General transcription factor IIH, polypeptide 2, 44 kDa, T-BTF2P44, TFIIH basal transcription factor complex p44 subunit,GTF2H2 / BTF2 / TFIIH Basal Transcription Factor
Cellular localisation: Nucleus - 分子量
- 44kDa
- 基因ID
- 2966, 607501
- UniProt
- Q13888
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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