GLUL 抗体 (AA 50-250)
Quick Overview for GLUL 抗体 (AA 50-250) (ABIN7126480)
抗原
See all GLUL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-250
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特异性
- Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
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交叉反应 （详细）
- Human. Horse. Cow.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 50-250) of human GLUL protein (exact sequence is proprietary)
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亚型
- IgG2b
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anti-Glutamate-Ammonia Ligase (GLUL) (AA 274-373) antibody
GLUL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) (AA 1-373) antibodyGLUL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) (AA 2-121) antibodyGLUL 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2D11A2 unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) antibodyMicroarray verified GLUL 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB178750 unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) (AA 70-96), (N-Term) antibodyGLUL 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21070 unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) (AA 86-373) antibodyGLUL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) antibodyMicroarray verified GLUL 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB545277 unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) (AA 1-373) antibodyGLUL 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) (C-Term) antibodyGLUL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Ammonia Ligase (GLUL) antibodyGLUL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human brain, stomach or thyroid. A-431 or Y79 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- GLUL (Glutamate-Ammonia Ligase (GLUL))
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别名
- GLUL
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背景
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Cell proliferation-inducing protein 59, GLUL, Glutamate ammonia ligase, GS, PIG43, PIG59, Glutamate decarboxylase, glutamine synthase, Glutamine synthetase, glutamine synthetase I, Proliferation inducing protein 43, GLNA, GLNS,Glutamine Synthetase / GLUL
Cellular localisation: Cytoplasm. Mitochondrion. -
分子量
- 42kDa
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基因ID
- 2752, 518525
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UniProt
- P15104
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
-
