FOXB1 抗体
Quick Overview for FOXB1 抗体 (ABIN7126475)
抗原
See all FOXB1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human FOXB1protein
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亚型
- IgG1
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FOXB1 (Forkhead Box B1 (FOXB1))
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别名
- FOXB1
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背景
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FKH 5, FKH5, Forkhead box B1, Forkhead box protein B1, FOX B1, FOXB 1, HFKH 5, HFKH-5, HFKH5, Transcription factor FKH 5, Transcription factor FKH5,FOXB1 (Transcription Factor)
Cellular localisation: Nucleus. -
分子量
- 35kDa
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基因ID
- 27023, 734475
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UniProt
- Q99853
抗原
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