GATA3 抗体
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- 抗原 See all GATA3 抗体
- GATA3 (GATA Binding Protein 3 (GATA3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GATA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50 kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67 % of urothelial Carcinomas, but none of prostate or renal carcinomas.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human GATA-3 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product GATA3 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human breast or urothelial carcinoma tissue.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- GATA3 (GATA Binding Protein 3 (GATA3))
- 别名
- GATA3 (GATA3 产品)
- 别名
- HDR antibody, HDRS antibody, Gata-3 antibody, jal antibody, cb550 antibody, gta3 antibody, GATA-3 antibody, XGATA3 antibody, xgata-3 antibody, hdr antibody, xGATA-3 antibody, GATA3 antibody, GATA transcription factor 3 antibody, T4L20.260 antibody, T4L20_260 antibody, gata3 antibody, ZH-DR antibody, zgc:103531 antibody, GATA binding protein 3 antibody, GATA binding protein 3 S homeolog antibody, GATA transcription factor 3 antibody, amidase antibody, putative amidase antibody, GATA-binding protein 3 antibody, hematopoietic death receptor antibody, GATA3 antibody, Gata3 antibody, gata3 antibody, gata3.S antibody, gatA3 antibody, hdr antibody
- 背景
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GATA binding protein-3, GATA-binding factor 3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Center) (Breast and Urothelial Marker)
Cellular localisation: Nuclear - 分子量
- 50kDa
- 基因ID
- 2625, 524134
- UniProt
- P23771
- 途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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