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GATA3 抗体

GATA3 适用: 人 WB, FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126462
发货至: 中国
  • 抗原 See all GATA3 抗体
    GATA3 (GATA Binding Protein 3 (GATA3))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This GATA3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50 kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67 % of urothelial Carcinomas, but none of prostate or renal carcinomas.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human GATA-3 protein
    亚型
    IgG2b
    Top Product
    Discover our top product GATA3 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human breast or urothelial carcinoma tissue.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    GATA3 (GATA Binding Protein 3 (GATA3))
    别名
    GATA3 (GATA3 产品)
    别名
    HDR antibody, HDRS antibody, Gata-3 antibody, jal antibody, cb550 antibody, gta3 antibody, GATA-3 antibody, XGATA3 antibody, xgata-3 antibody, hdr antibody, xGATA-3 antibody, GATA3 antibody, GATA transcription factor 3 antibody, T4L20.260 antibody, T4L20_260 antibody, gata3 antibody, ZH-DR antibody, zgc:103531 antibody, GATA binding protein 3 antibody, GATA binding protein 3 S homeolog antibody, GATA transcription factor 3 antibody, amidase antibody, putative amidase antibody, GATA-binding protein 3 antibody, hematopoietic death receptor antibody, GATA3 antibody, Gata3 antibody, gata3 antibody, gata3.S antibody, gatA3 antibody, hdr antibody
    背景
    GATA binding protein-3, GATA-binding factor 3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Center) (Breast and Urothelial Marker)
    Cellular localisation: Nuclear
    分子量
    50kDa
    基因ID
    2625, 524134
    UniProt
    P23771
    途径
    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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