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CNOT10 抗体

CNOT10 适用: 人 WB, ELISA, IF, IP, Coat, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126458
发货至: 中国
  • 抗原 See all CNOT10 products
    CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))
    适用
    • 17
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    宿主
    • 15
    • 2
    小鼠
    克隆类型
    • 17
    单克隆
    标记
    • 10
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    • 1
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    This CNOT10 antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS)
    特异性
    CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human CNOT10 protein
    亚型
    IgG2
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or HepG2 cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))
    别名
    CNOT10 (CNOT10 产品)
    别名
    2600001P13Rik antibody, cnot10 antibody, im:7139356 antibody, zgc:152939 antibody, cnot10-a antibody, cnot10-b antibody, CCR4-NOT transcription complex subunit 10 antibody, CCR4-NOT transcription complex, subunit 10 antibody, CCR4-NOT transcription complex subunit 10 S homeolog antibody, CCR4-NOT transcription complex subunit 10 L homeolog antibody, CNOT10 antibody, Cnot10 antibody, cnot10.S antibody, cnot10 antibody, cnot10.L antibody
    背景
    FLJ12890, FLJ13165,CCR4-NOT transcription complex, subunit 10 (CNOT10)
    Cellular localisation: Cytoplasm. Mitochondrion and Nucleus, PML body.
    分子量
    82.31kDa
    基因ID
    25904, 444851
    UniProt
    Q9H9A5