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SIRT3 抗体

This anti-SIRT3 antibody is a 小鼠 单克隆 antibody detecting SIRT3 in WB, ELISA, IP, IF, FACS 和 Coat. Suitable for 人.
产品编号 ABIN7126428
发货至: 中国

Quick Overview for SIRT3 抗体 (ABIN7126428)

抗原

See all SIRT3 抗体
SIRT3 (Sirtuin 3 (SIRT3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SIRT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
  • 特异性

    Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human SIRT3 protein

    亚型

    IgG2a
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    SIRT3 (Sirtuin 3 (SIRT3))

    别名

    SIRT3

    背景

    HSIRT3, Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase, NAD dependent deacetylase sirtuin 3 mitochondrial, Regulatory protein SIR2 homolog 3, SIR2 like protein 3, SIR2-like protein 3, SIR2L3, Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae), Sirtuin type 3, Sirtuin3,Sirtuin 3 (SIRT3)
    Cellular localisation: Mitochondrion matrix.

    分子量

    43.57kDa

    基因ID

    23410, 716456

    UniProt

    Q9NTG7
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