Recombinant SATB2 抗体 (AA 200-300)
Quick Overview for Recombinant SATB2 抗体 (AA 200-300) (ABIN7126417)
抗原
See all SATB2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-300
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特异性
- SATB2 is a DNA binding protein that specifically binds nuclear matrix attachment regions. It is involved in transcription regulation and chromatin remodeling. SATB2 expression in colorectal carcinomas (CRC) is correlated with good prognosis and in laryngeal squamous cell carcinoma it functions as a tumor suppressor wherein loss of expression is positively correlated with high tumor grade and recurrence. Moreover, SATB2, in combination with CK20, could identify almost all CRC s. Upper gastrointestinal (GI) carcinomas and pancreatic ductal carcinomas are usually negative for SATB2, and ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origin are rarely positive for SATB2. Additionally, SATB2 antibody can identify neuroendocrine neoplasms of colon and rectum because SATB2 is usually negative in neuroendocrine neoplasms of the GI tract, pancreas, and lung. More recently, it has been reported that SATB2 is a sensitive marker for tumors with osteoblastic differentiation.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa200-300) of human SATB2 protein (exact sequence is proprietary)
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亚型
- IgG1
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anti-SATB Homeobox 2 (SATB2) antibody
SATB2 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-SATB Homeobox 2 (SATB2) (AA 377-499) antibodySATB2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7B2E11 unconjugated
anti-SATB Homeobox 2 (SATB2) antibodyMicroarray verified SATB2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB247463 unconjugated
anti-SATB Homeobox 2 (SATB2) antibodyMicroarray verified SATB2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB382113 unconjugated
anti-SATB Homeobox 2 (SATB2) (AA 451-485) antibodySATB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 2 (SATB2) (AA 228-369) antibodySATB2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 2 (SATB2) (AA 540-620) antibodySATB2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 2 (SATB2) (AA 200-300) antibodySATB2 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-702R unconjugated Recombinant Antibody
anti-SATB Homeobox 2 (SATB2) antibodySATB2 适用: 人 WB, IP, ICC, DB 宿主: 小鼠 Monoclonal SATBA4B10 unconjugated
anti-SATB Homeobox 2 (SATB2) (C-Term) antibodySATB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human colon or cerebral cortex tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- SATB2 (SATB Homeobox 2 (SATB2))
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别名
- SATB2
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背景
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DNA-binding protein SATB2, GLSS, SATB homeobox 2, Special AT-rich sequence-binding protein 2,SATB2 (Colorectal Carcinoma Marker)
Cellular localisation: Nuclear -
分子量
- 83kDa
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基因ID
- 23314, 516617
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UniProt
- Q9UPW6
抗原
-
