Recombinant Filaggrin 抗体 (AA 198-288)
Quick Overview for Recombinant Filaggrin 抗体 (AA 198-288) (ABIN7126404)
抗原
See all Filaggrin (FLG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 198-288
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特异性
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human Filaggrin protein fragment (around aa 198-288) (exact sequence is proprietary)
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亚型
- IgG
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anti-Filaggrin (FLG) (AA 119-336) antibody
FLG 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 998-1104) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1563 unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1561 unconjugated
anti-Filaggrin (FLG) (AA 3838-4061) antibodyFLG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 兔 Monoclonal FLG-1957R unconjugated Recombinant Antibody
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal rFLG-1561 unconjugated Recombinant Antibody
anti-Filaggrin (FLG) antibodyFLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 3905-4031) antibodyFLG 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (pTyr654) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (pTyr154) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (2-4 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: U-251-MGor A-431 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Filaggrin (FLG)
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别名
- FLG
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背景
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ATOD2, Epidermal Filaggrin, Filaggrin, Filaggrin precursor, Fillagrin, FLG, Profilaggrin,Filaggrin (Keratinocyte Differentiation Marker)
Cellular localisation: Cytoplasm -
分子量
- 26-45kDa (Processed), 350kDa (Profilaggrin)
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基因ID
- 2312, 654510
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UniProt
- P20930
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途径
- Sensory Perception of Sound, Stem Cell Maintenance
抗原
-
