FOXL1 抗体 (AA 104-258)
Quick Overview for FOXL1 抗体 (AA 104-258) (ABIN7126396)
抗原
See all FOXL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 104-258
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特异性
- FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.
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交叉反应 （详细）
- Human. Predicted to react in Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa104-258) of human FOXL1 protein (exact sequence is proprietary)
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亚型
- IgG1
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anti-Forkhead Box L1 (FOXL1) (AA 1-345) antibody
FOXL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box L1 (FOXL1) (AA 132-240) antibodyFOXL1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Forkhead Box L1 (FOXL1) (AA 132-240) antibodyFOXL1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-Forkhead Box L1 (FOXL1) (AA 221-319) antibodyFOXL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-Forkhead Box L1 (FOXL1) antibodyFOXL1 适用: 人, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box L1 (FOXL1) (Internal Region) antibodyFOXL1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box L1 (FOXL1) (N-Term) antibodyFOXL1 适用: 人, 小鼠, Cow, 犬, Pig, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box L1 (FOXL1) (N-Term) antibodyFOXL1 适用: 人, 小鼠, Cow, 犬, Pig, 马, 兔, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box L1 (FOXL1) (Internal Region) antibodyFOXL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box L1 (FOXL1) antibodyFOXL1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FOXL1 (Forkhead Box L1 (FOXL1))
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别名
- FOXL1
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背景
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FKHL10, FREAC6, JFJ-3, FKH6, FKH11, Forkhead box protein L1, Forkhead related transcription factor, FREAC7,FOXL1 / Forkhead Box Protein L1 (Transcription Factor)
Cellular localisation: Nucleus. -
分子量
- 36-41kDa
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基因ID
- 2299, 87236
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UniProt
- Q12951
抗原
-
