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FABP1 抗体 (AA 1-127)

This anti-FABP1 antibody is a 小鼠 单克隆 antibody detecting FABP1 in WB, IHC 和 IHC (f). Suitable for 人.
产品编号 ABIN7126373
发货至: 中国

Quick Overview for FABP1 抗体 (AA 1-127) (ABIN7126373)

抗原

See all FABP1 抗体
FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

适用

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宿主

  • 86
  • 39
  • 1
  • 1
小鼠

克隆类型

  • 87
  • 40
单克隆

标记

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  • 2
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This FABP1 antibody is un-conjugated

应用范围

  • 90
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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

    • 39
    • 15
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 1-127

    特异性

    Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)

    亚型

    IgG2a
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Liver or colon carcinoma tissues (IHC). Kidney tissue lysates (WB).

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

    别名

    FABP1

    背景

    FABP1, L-FABP,Fatty Acid Binding Protein (Liver) / FABP1
    Cellular localisation: Cytoplasm. Nuclear.

    分子量

    14kDa

    基因ID

    2168, 380135

    UniProt

    P07148

    途径

    Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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