FABP1 抗体 (AA 1-127)
Quick Overview for FABP1 抗体 (AA 1-127) (ABIN7126371)
抗原
See all FABP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-127
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特异性
- Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)
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亚型
- IgG2b
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应用备注
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Known_Application: Western Blot (2-4 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Liver or colon carcinoma tissues (IHC). Human kidney tissue lysate (WB).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))
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别名
- FABP1
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背景
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FABP1, L-FABP,Fatty Acid Binding Protein (Liver) / FABP1
Cellular localisation: Cytoplasm. Nucleus. -
分子量
- 14kDa
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基因ID
- 2168, 380135
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UniProt
- P07148
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途径
- Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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