CD5L 抗体 (AA 269-366)
Quick Overview for CD5L 抗体 (AA 269-366) (ABIN7126363)
抗原
See all CD5L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 269-366
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特异性
- CD5L (CD5 Molecule-like), also known as API6, PRO229, Spi± or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Ramos, or MOLT-4 cells. Human tonsil or lymph node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD5L (CD5 Molecule-Like (CD5L))
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别名
- CD5L
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背景
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AAC-11, AIM, API6, APOPTOSIS INHIBITOR 6, APOPTOSIS INHIBITOR OF MACROPHAGES, CD5 antigen like (scavenger receptor cysteine rich family), CD5 antigen-like, CT-2, Highly similar to ANTIGEN WC1.1 [Bos taurus], IgM-associated peptide, Pdp, PRO229, SCAVENGER RECEPTOR CYSTEINE-RICH FAMILY, SP-alpha, Spalpha,CD5L / CD5LG / CD5 Ligand
Cellular localisation: Secreted. -
分子量
- 38kDa
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基因ID
- 922, 134035
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UniProt
- O43866
抗原
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