Fetuin A 抗体
Quick Overview for Fetuin A 抗体 (ABIN7126323)
抗原
See all Fetuin A (AHSG) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Fetuin (also designated i±2-z-globulin or i±2-HS-glycoprotein) is a secreted plasma protein that is expressed in hepatocytes, monocyte/macrophages and in bone and is downregulated during injury and inflammation. Fetuin preferentially binds to and carries calcium and barium ions in the blood, where it is thought to mediate serum calcium homeostasis and mineralization, and to potentially participate in the transport of bioactive molecules. Additionally, fetuin has been shown to function as an acute phase anti-inflammatory mediator that is critical to regulating the innate immune response following tissue injury. During inflammation, circulating fetuin levels substantially decrease as fetuin becomes associated with the membranes of macrophages. This membrane associated form of fetuin acts as an opsonic participant by potentiating the entry of cationic small molecules into the activated macro-phage, which in turn facilitates macrophage-deactivating mechanisms. Biologically active fetuin is derived from a precursor protein that is cleaved at the aminoterminus to generate two chains held together by a single disulfide bond.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human AHSG protein (exact sequence is proprietary)
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亚型
- IgG1
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anti-alpha-2-HS-Glycoprotein (AHSG) (AA 200-240) antibody (AbBy Fluor® 594)
AHSG 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal AbBy Fluor® 594
anti-alpha-2-HS-Glycoprotein (AHSG) (AA 19-250) antibodyAHSG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) antibodyAHSG 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) (AA 201-300) antibodyAHSG 适用: 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) (AA 247-276), (C-Term) antibodyAHSG 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18674 unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) (AA 19-359) antibodyAHSG 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) (AA 19-367) antibodyAHSG 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) antibodyAHSG 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) antibodyAHSG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-HS-Glycoprotein (AHSG) (AA 1-367) antibodyAHSG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human liver, testisor placenta.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))
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别名
- AHSG
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背景
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59 kDa bone sialic acid-containing protein, Aa2-066, AHS, A-2-HS-glycoprotein chain B, Alpha-2-Z-globulin, HSGA Asialofetuin, Ba-alpha-2-glycoprotein, BSP, Countertrypin, Fetua, Fetuin A, Glycoprotein PP63,Fetuin / AHSG (alpha 2-HS glycoprotein)
Cellular localisation: Secreted. -
分子量
- 59kDa
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基因ID
- 197, 324746
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UniProt
- P02765
抗原
-
