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Reelin 抗体 (AA 1796-2115)

RELN 适用: 人 WB, IP, ELISA, IF, Coat, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126322
发货至: 中国
  • 抗原 See all Reelin (RELN) 抗体
    Reelin (RELN)
    抗原表位
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1796-2115
    适用
    • 36
    • 24
    • 9
    宿主
    • 36
    • 9
    • 2
    • 1
    小鼠
    克隆类型
    • 30
    • 18
    单克隆
    标记
    • 25
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Reelin antibody is un-conjugated
    应用范围
    • 29
    • 24
    • 13
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.
    交叉反应 (详细)
    Human, Mouse and Rodent.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa 1796-2115) of human RELN protein
    亚型
    IgG2b
    Top Product
    Discover our top product RELN Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human or mouse brain or CNS.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Reelin (RELN)
    别名
    RELN (RELN 产品)
    别名
    LIS2 antibody, PRO1598 antibody, RL antibody, reeler antibody, rl antibody, Reelen antibody, Rl antibody, reln antibody, RELN antibody, MGC172539 antibody, reelin antibody, reelin L homeolog antibody, RELN antibody, Reln antibody, reln antibody, reln.L antibody, LOC579060 antibody
    背景
    LIS2, PRO1598, Reeler, Reelin, RELN, RELN_HUMAN, RL,Reelin
    Cellular localisation: Cytoplasm
    分子量
    387.5kDa
    基因ID
    19699, 655654
    UniProt
    P78509
    途径
    Synaptic Membrane
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