EIF2S1 抗体
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- 抗原 See all EIF2S1 抗体
- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EIF2S1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2a, eIF2band eIF2g (eukaryotic translation initiation factor 2 a, band g, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2a, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2a controls the rate of tRNA translation. When eIF2a is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2a is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
- 交叉反应 （详细）
- Human. Predicted to work in Rat and Zebrafish.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human EIF2S1 protein
- 亚型
- IgG2a
- Top Product
- Discover our top product EIF2S1 Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) antibody
EIF2S1 适用: 人 WB, IF, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H12-C11 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibodyEIF2S1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A5 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (N-Term) antibodyEIF2S1 适用: 人, 小鼠, 大鼠, Pig WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibodyEIF2S1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Monoclonal 1C6 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer49) antibodyEIF2S1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibodyEIF2S1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 276-315) antibodyEIF2S1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or MCF7 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
- 别名
- EIF2S1 (EIF2S1 产品)
- 背景
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Eukaryotic translation initiation factor 2 subunit 1 alpha 35 kDa (EIF2S1), EIF-2alpha, EIF2, EIF2A,EIF2S1 / EIF-2 alpha (EIF2A)
Cellular localisation: Nucleus. - 分子量
- 36kDa
- 基因ID
- 1965, 151777
- UniProt
- P05198
- 途径
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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