AKR1C1 抗体
Quick Overview for AKR1C1 抗体 (ABIN7126291)
抗原
See all AKR1C1 (DDH) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length AKR1C1 protein
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亚型
- IgG1
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anti-Dihydrodiol Dehydrogenase (DDH) antibody
KO Validated DDH 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (AA 1-110) antibodyDDH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (AA 1-323) antibodyDDH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (AA 1-110) antibodyDDH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (AA 1-323) antibodyDDH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) antibodyDDH 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT6D10 unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (AA 219-323) antibodyDDH 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) antibodyDDH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (AA 1-323) antibodyDDH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dihydrodiol Dehydrogenase (DDH) (N-Term) antibodyDDH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 or A549 cells. Human liver or stomach tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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别名
- AKR1C1
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背景
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2-dihydrobenzene-1, 2-diol dehydrogenase, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, C9, Chlordecone reductase homolog HAKRC, DD1/DD2, DDH1, Dihydrodiol dehydrogenase 1/2, H37, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase, Type II 3 alpha hydroxysteroid dehydrogenase,Aldo-keto Reductase Family 1 Member C1 / DD1
Cellular localisation: Cytoplasm. -
分子量
- 37kDa
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基因ID
- 1645, 460260
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UniProt
- Q04828
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
-
