ZBTB46 抗体
Quick Overview for ZBTB46 抗体 (ABIN7126257)
抗原
See all ZBTB46 (ZNF340) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
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交叉反应 （详细）
- Human. Predicted to react with Mouse and Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human ZBTB46 protein
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亚型
- IgG2a
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anti-Zinc Finger Protein 340 (ZNF340) (AA 174-362) antibody
ZNF340 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 340 (ZNF340) (AA 1-589) antibodyZNF340 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 340 (ZNF340) (AA 179-228) antibodyZNF340 适用: 人, 小鼠, 大鼠, Cow, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 340 (ZNF340) (N-Term) antibodyZNF340 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 340 (ZNF340) (N-Term) antibodyZNF340 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil, brain or rectum. HeLa or U-2 OS cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))
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别名
- ZBTB46
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背景
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BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340,ZBTB46 / BTBD4 / ZNF340
Cellular localisation: Nucleus -
分子量
- 64kDa
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基因ID
- 140685, 585028
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UniProt
- Q86UZ6
抗原
-
