LRG1 抗体 (AA 30-180)
Quick Overview for LRG1 抗体 (AA 30-180) (ABIN7126225)
抗原
See all LRG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-180
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特异性
- LRG1 (leucine-rich i±2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains 8 LRR (leucine-rich) repeats and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 30-180) of human LRG1 protein (exact sequence is proprietary)
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亚型
- IgG2b
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human liver, pancreas or breast.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
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别名
- LRG1
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背景
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1300008B03Rik, 2310031E04Rik, A2GL, HMFT1766, Leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor, LRG1,LRG1 / Leucine Rich alpha-2-glycoprotein 1
Cellular localisation: Secreted. -
分子量
- 38kDa
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基因ID
- 116844, 655559
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UniProt
- P02750
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途径
- Brown Fat Cell Differentiation
抗原
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