CKM 抗体
Quick Overview for CKM 抗体 (ABIN7126222)
抗原
See all CKM 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length CKM protein
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亚型
- IgG2a
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Human heart tissue. Skeletal muscle lysate.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CKM (Creatine Kinase, Muscle (CKM))
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别名
- CKM
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背景
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CKM, CKMM, Creatine kinase M, Creatine kinase M chain, Creatine kinase M type, Creatine kinase M-type, Creatine kinase muscle, Creatine kinase, muscle type, M-CK, MCK, Muscle creatine kinase,Creatine Kinase MM
Cellular localisation: Cytoplasm -
分子量
- 43kDa
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基因ID
- 1158, 334347
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UniProt
- P06732
抗原
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