ECD/SGT1 抗体
Quick Overview for ECD/SGT1 抗体 (ABIN7126219)
抗原
See all ECD/SGT1 (ECD) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
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交叉反应 （详细）
- Human. Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan and Elephant (based on sequence homology).
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human ECD protein
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亚型
- IgG2b
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anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibody
ECD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-300) antibodyECD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibodyECD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (C-Term) antibodyECD 适用: 人, 山羊, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 72-121) antibodyECD 适用: 人, 山羊, 马, 兔, Cow, Pig, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or 293T cells. Human testis, spleen or colon.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
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别名
- ECD
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背景
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Ecdysoneless homolog, hSGT1, Human suppressor of GCR two, Protein ecdysoneless homolog, SGT1 protein,ECD / SGT1
Cellular localisation: Nucleus. Cytosol. -
分子量
- 72.76kDa
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基因ID
- 11319, 631822
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UniProt
- O95905
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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