IRF9 抗体
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- 抗原 See all IRF9 抗体
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IRF9 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- 交叉反应 (详细)
- Human
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human IRF9 protein
- 亚型
- IgG2a
- Top Product
- Discover our top product IRF9 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, Jurkat or K562 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- 别名
- IRF9 (IRF9 产品)
- 别名
- IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
- 背景
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IFN alpha responsive transcription factor subunit, Interferon regulatory factor 9, Interferon-stimulated gene factor 3 gamma, interferon-stimulated transcription factor 3, gamma 48 kDa, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, ISGF3G, p48, Transcriptional regulator ISGF3 subunit gamma,Interferon regulatory factor 9 / IRF-9
Cellular localisation: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. - 分子量
- 43.34kDa
- 基因ID
- 10379, 1706
- UniProt
- Q00978
- 途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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