TOM1L1 抗体
Quick Overview for TOM1L1 抗体 (ABIN7126158)
抗原
See all TOM1L1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human TOM1L1 protein
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亚型
- IgG
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Human kidney.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))
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别名
- TOM1L1
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背景
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2310045L10Rik, C80573, OK/KNS CL.3, Src activating and signaling molecule, SRCASM, Target of Myb like protein 1, Target of myb1 (chicken) homolog like 1, Target of myb1 (chicken) like 1, TOM1 like protein 1, TOM1L1 protein,TOM1L1 (Target of Myb1 Like 1 Membrane Trafficking Protein)
Cellular localisation: Golgi apparatus > Golgi stack. Endosome membrane. -
分子量
- 53kDa.
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基因ID
- 10040, 153504
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UniProt
- O75674
抗原
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