ZKSCAN3 抗体
Quick Overview for ZKSCAN3 抗体 (ABIN7120976)
抗原
See all ZKSCAN3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ZKSCAN3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- zinc finger with KRAB and SCAN domains 3
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))
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别名
- ZKSCAN3
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背景
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Synonyms: Zinc finger protein with KRAB and SCAN domains 3|Zinc finger and SCAN domain-containing protein 13|Zinc finger protein 306|Zinc finger protein 309|Zinc finger protein 47 homolog (Zf47, Zfp-47)|ZKSCAN3|ZFP47|ZNF306|ZNF309|ZSCAN13
Background: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
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分子量
- 62 kDa
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基因ID
- 80317
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UniProt
- Q9BRR0
抗原
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