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ZNF238 抗体

This anti-ZNF238 antibody is a 兔 多克隆 antibody detecting ZNF238 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120963
发货至: 中国

Quick Overview for ZNF238 抗体 (ABIN7120963)

抗原

See all ZNF238 抗体
ZNF238 (Zinc Finger Protein 238 (ZNF238))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ZNF238 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    zinc finger protein 238

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ZNF238 (Zinc Finger Protein 238 (ZNF238))

    别名

    ZNF238

    背景

    Synonyms:58 kDa repressor protein, C2H2 171, RP58, TAZ 1, TAZ1, Transcriptional repressor RP58, ZBTB18, ZFP238, zinc finger protein 238, Zinc finger protein C2H2 171, ZNF238 Background:ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD. Specific binding is found for a 60- kDa band which corresponds to the full length of RP58 protein. In addition, a 48- kDa band, thought to be the truncated form 2 is detected(PMID: 9756912).

    分子量

    48 kDa

    UniProt

    Q99592
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