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YTHDF1 抗体 (AA 133-349)

This anti-YTHDF1 antibody is a 兔 多克隆 antibody detecting YTHDF1 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120903
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for YTHDF1 抗体 (AA 133-349) (ABIN7120903)

抗原

YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

适用

  • 23
  • 12
  • 9
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26

克隆类型

  • 21
  • 5
多克隆

标记

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This YTHDF1 antibody is un-conjugated

应用范围

  • 17
  • 9
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 133-349

    原理

    YTHDF1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 133-349aa

    Immunogen: YTH domain family, member 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

    别名

    YTHDF1

    背景

    Synonyms: YTH domain-containing family protein 1 (DF1)|Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1)|YTHDF1|C20orf21

    Background: Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).

    分子量

    62 kDa

    基因ID

    54915

    UniProt

    Q9BYJ9
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