YTHDF1 抗体 (AA 133-349)
Quick Overview for YTHDF1 抗体 (AA 133-349) (ABIN7120903)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-349
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原理
- YTHDF1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 133-349aa
Immunogen: YTH domain family, member 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
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别名
- YTHDF1
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背景
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Synonyms: YTH domain-containing family protein 1 (DF1)|Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1)|YTHDF1|C20orf21
Background: Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).
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分子量
- 62 kDa
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基因ID
- 54915
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UniProt
- Q9BYJ9
抗原
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