YTHDC2 抗体 (AA 1131-1430)
Quick Overview for YTHDC2 抗体 (AA 1131-1430) (ABIN7120902)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1131-1430
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原理
- YTHDC2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1131-1430aa
Immunogen: 3'-5' RNA helicase YTHDC2
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亚型
- IgG
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anti-YTH Domain Containing 2 (YTHDC2) (AA 1131-1430) antibody
YTHDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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别名
- YTHDC2
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背景
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Synonyms: 3'-5' RNA helicase YTHDC2|YTH domain-containing protein 2 (hYTHDC2)|YTHDC2
Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
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分子量
- 160 kDa
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基因ID
- 64848
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UniProt
- Q9H6S0
抗原
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