WWP1 抗体
Quick Overview for WWP1 抗体 (ABIN7120866)
抗原
See all WWP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- WWP1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- WW domain containing E3 ubiquitin protein ligase 1
-
亚型
- IgG
-
-
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibody
WWP1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-260) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibodyWWP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibodyWWP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (Internal Region) antibodyWWP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) antibodyWWP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-260) antibodyWWP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-922) antibodyWWP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 152-261) antibodyWWP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (N-Term) antibodyWWP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:200-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
-
别名
- WWP1
-
背景
-
Synonyms: NEDD4-like E3 ubiquitin-protein ligase WWP1|Atrophin-1-interacting protein 5 (AIP5)|HECT-type E3 ubiquitin transferase WWP1|TGIF-interacting ubiquitin ligase 1 (Tiul1)|WW domain-containing protein 1|WWP1
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
-
分子量
- 90-110 kDa
-
基因ID
- 11059
-
UniProt
- Q9H0M0
抗原
-
