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WT1 抗体

This anti-WT1 antibody is a 兔 多克隆 antibody detecting WT1 in IHC, IF, WB, ELISA 和 IP. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7120843
发货至: 中国

Quick Overview for WT1 抗体 (ABIN7120843)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

适用

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人, 大鼠, 小鼠

宿主

  • 105
  • 70
  • 1

克隆类型

  • 99
  • 77
多克隆

标记

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  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WT1 antibody is un-conjugated

应用范围

  • 90
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  • 5
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Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Wilms tumor 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:50-1:500, IF: 1:20-1:200, IP: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    WT1

    背景

    Synonyms:GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT 2, WT1, WT33 Background:Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

    分子量

    52 kDa

    基因ID

    7490

    UniProt

    P19544

    途径

    Tube Formation
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