WT1 抗体
Quick Overview for WT1 抗体 (ABIN7120843)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- WT1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- Wilms tumor 1
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:5000, IHC: 1:50-1:500, IF: 1:20-1:200, IP: 1:500-1:5000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- WT1 (Wilms Tumor 1 (WT1))
-
别名
- WT1
-
背景
-
Synonyms: Wilms tumor protein|WT33|WT1
Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
-
分子量
- 52 kDa
-
基因ID
- 7490
-
UniProt
- P19544
-
途径
- Tube Formation
抗原
-