WDR24 抗体
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北京 101111
Quick Overview for WDR24 抗体 (ABIN7120816)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- WDR24 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- WD repeat domain 24
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亚型
- IgG
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anti-WD Repeat Domain 24 (WDR24) (AA 1-298) antibody
WDR24 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- WDR24 (WD Repeat Domain 24 (WDR24))
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别名
- WDR24
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背景
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Synonyms: GATOR2 complex protein WDR24|WD repeat-containing protein 24|WDR24|C16orf21
Background: As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).
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分子量
- 102 kDa
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基因ID
- 84219
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UniProt
- Q96S15
抗原
-
