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WDR24 抗体

This anti-WDR24 antibody is a 兔 多克隆 antibody detecting WDR24 in ELISA, WB, IHC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN7120816
发货至: 中国

Quick Overview for WDR24 抗体 (ABIN7120816)

抗原

WDR24 (WD Repeat Domain 24 (WDR24))

适用

  • 9
  • 1
  • 1
人, 小鼠

宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 6
  • 1
  • 1
  • 1
This WDR24 antibody is un-conjugated

应用范围

  • 6
  • 5
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  • 1
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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    WD repeat domain 24

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    WDR24 (WD Repeat Domain 24 (WDR24))

    别名

    WDR24

    背景

    Synonyms:C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24 Background:As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).

    分子量

    102 kDa

    基因ID

    84219

    UniProt

    Q96S15
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