WRAP53 抗体
Quick Overview for WRAP53 抗体 (ABIN7120809)
抗原
See all WRAP53 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- WD repeat containing, antisense to TP53
-
亚型
- IgG
-
-
anti-WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 62-160) antibody
WRAP53 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 1-548) antibodyWRAP53 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 1-548) antibodyWRAP53 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 285-390) antibodyWRAP53 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
-
别名
- WRAP53
-
背景
- Synonyms:FLJ10385, TCAB1, WDR79, WRAP53 Background:Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
-
分子量
- 72 kDa
-
基因ID
- 55135
-
UniProt
- Q9BUR4
-
途径
- Telomere Maintenance
抗原
-
