WDFY3 抗体
Quick Overview for WDFY3 抗体 (ABIN7120806)
抗原
See all WDFY3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WDFY3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- WD repeat and FYVE domain containing 3
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亚型
- IgG
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应用备注
- IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))
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别名
- WDFY3
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背景
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Synonyms: WD repeat and FYVE domain-containing protein 3|Autophagy-linked FYVE protein (Alfy)|WDFY3|KIAA0993
Background: Required for selective autophagy(aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
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基因ID
- 23001
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UniProt
- Q8IZQ1
抗原
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