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Villin 1 抗体

This anti-Villin 1 antibody is a 小鼠 单克隆 antibody detecting Villin 1 in IHC, WB, IF, ELISA 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7120768
发货至: 中国

Quick Overview for Villin 1 抗体 (ABIN7120768)

抗原

See all Villin 1 (VIL1) 抗体
Villin 1 (VIL1)

适用

  • 119
  • 24
  • 20
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 61
  • 58
小鼠

克隆类型

  • 80
  • 39
单克隆

标记

  • 57
  • 8
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
This Villin 1 antibody is un-conjugated

应用范围

  • 72
  • 49
  • 43
  • 20
  • 17
  • 12
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

克隆位点

3D11
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    villin 1

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:50-1:2000, IF: 1:10-1:100, IP: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Villin 1 (VIL1)

    别名

    Villin

    背景

    Synonyms:VIL, VIL1, Villin, villin 1 Background:Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.

    分子量

    93 kDa

    基因ID

    7429

    UniProt

    P09327

    途径

    EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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