VAMP8 抗体 (AA 1-75)
Quick Overview for VAMP8 抗体 (AA 1-75) (ABIN7120762)
抗原
See all VAMP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-75
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原理
- VAMP8 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-75aa
Immunogen: vesicle-associated membrane protein 8(endobrevin)
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))
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别名
- VAMP8
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背景
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Synonyms: Vesicle-associated membrane protein 8 (VAMP-8)|Endobrevin (EDB)|VAMP8
Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).
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分子量
- 15 kDa
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基因ID
- 8673
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UniProt
- Q9BV40
抗原
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