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VAMP8 抗体 (AA 1-75)

This anti-VAMP8 antibody is a 兔 多克隆 antibody detecting VAMP8 in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7120762
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VAMP8 抗体 (AA 1-75) (ABIN7120762)

抗原

See all VAMP8 抗体
VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This VAMP8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1-75

    原理

    VAMP8 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-75aa

    Immunogen: vesicle-associated membrane protein 8(endobrevin)

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

    别名

    VAMP8

    背景

    Synonyms: Vesicle-associated membrane protein 8 (VAMP-8)|Endobrevin (EDB)|VAMP8

    Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).

    分子量

    15 kDa

    基因ID

    8673

    UniProt

    Q9BV40
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