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VAMP7 抗体

The 兔 多克隆 anti-VAMP7 antibody (ABIN7120761) specifically detects VAMP7 in ELISA, WB, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7120761
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VAMP7 抗体 (ABIN7120761)

抗原

See all VAMP7 抗体
VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This VAMP7 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    VAMP7 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    vesicle-associated membrane protein 7

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200,IF: 1:10-1:100, IP: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

    别名

    VAMP7

    背景

    Synonyms: Vesicle-associated membrane protein 7 (VAMP-7)|Synaptobrevin-like protein 1|Tetanus-insensitive VAMP (Ti-VAMP)|VAMP7|SYBL1

    Background: VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7.

    分子量

    20 kDa, 50 kDa

    UniProt

    P51809
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