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VAMP7 抗体

This anti-VAMP7 antibody is a 兔 多克隆 antibody detecting VAMP7 in ELISA, WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120761
发货至: 中国

Quick Overview for VAMP7 抗体 (ABIN7120761)

抗原

See all VAMP7 抗体
VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

适用

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人, 小鼠, 大鼠

宿主

  • 60
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克隆类型

  • 62
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多克隆

标记

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This VAMP7 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    vesicle-associated membrane protein 7

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200,IF: 1:10-1:100, IP: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

    别名

    VAMP7/TI-VAMP

    背景

    Synonyms:SYBL1, Synaptobrevin like protein 1, Tetanus insensitive VAMP, TI VAMP, TI-VAMP, VAMP 7, VAMP7 Background:VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7.

    分子量

    20 kDa, 50 kDa

    UniProt

    P51809
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