VPS26A 抗体
Quick Overview for VPS26A 抗体 (ABIN7120721)
抗原
See all VPS26A 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- vacuolar protein sorting 26 homolog A
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亚型
- IgG
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anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (C-Term) antibody
Verified VPS26A 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 228-327) antibodyVPS26A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 21-180) antibodyVPS26A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) antibodyVPS26A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 208-327) antibodyVPS26A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (C-Term) antibodyVPS26A 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 263-291) antibodyVPS26A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22339 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) antibodyVPS26A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) antibodyVPS26A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 1-327) antibodyVPS26A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- VPS26A (Vacuolar Protein Sorting-Associated Protein 26A (VPS26A))
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别名
- VPS26A
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背景
- Synonyms:FLJ12930, HB58, Hbeta58, hVPS26, PEP8A, Vesicle protein sorting 26A, VPS26, VPS26A Background:Acts as component of the retromer cargo-selective complex(CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins(Probable). The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5(Probable). Required for retrograde transport of lysosomal enzyme receptor IGF2R(PubMed:15078902, PubMed:15078903). Required to regulate transcytosis of the polymeric immunoglobulin receptor(pIgR-pIgA)(PubMed:15247922). Required for the endosomal localization of FAM21A(indicative for the WASH complex)(PubMed:22070227). Required for the endosomal localization of TBC1D5(PubMed:20923837). Mediates retromer cargo reognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP(PubMed:22279231). Involved in retromer-independent lysosomal sorting of F2R(PubMed:16407403). Involved in recycling of ADRB2(PubMed:21602791). Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins(By similarity).
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分子量
- 38 kDa
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基因ID
- 9559
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UniProt
- O75436
抗原
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