VPS4B 抗体
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北京 101111
Quick Overview for VPS4B 抗体 (ABIN7120711)
抗原
See all VPS4B (vps4b) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- VPS4B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- vacuolar protein sorting 4 homolog B
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亚型
- IgG
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anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 1-117) antibody
vps4b 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 1-444) antibodyvps4b 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 1-85) antibodyvps4b 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 304-332), (C-Term) antibodyvps4b 适用: 人 WB 宿主: 兔 Polyclonal RB32061 unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (N-Term) antibodyvps4b 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 70-119) antibodyvps4b 适用: 人, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000,IP: 1:500-1:5000,IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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别名
- VPS4B
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背景
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Synonyms: Vacuolar protein sorting-associated protein 4B|Cell migration-inducing gene 1 protein|Suppressor of K(+) transport growth defect 1 (Protein SKD1)|VPS4B|SKD1|VPS42
Background: Involved in late steps of the endosomal multivesicular bodies(MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding(HIV-1 and other lentiviruses). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413).
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分子量
- 50 kDa
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基因ID
- 9525
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UniProt
- O75351
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途径
- Microtubule Dynamics, CXCR4-mediated Signaling Events
抗原
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