VPS33A 抗体
This anti-VPS33A antibody is a 兔 多克隆 antibody detecting VPS33A in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for VPS33A 抗体 (ABIN7120707)
抗原
See all VPS33A 抗体
VPS33A
(Vacuolar Protein Sorting 33 Homolog A (VPS33A))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This VPS33A antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- vacuolar protein sorting 33 homolog A(S. cerevisiae)
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亚型
- IgG
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anti-Vacuolar Protein Sorting 33 Homolog A (VPS33A) (AA 1-596) antibody
VPS33A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 33 Homolog A (VPS33A) (AA 1-300) antibodyVPS33A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- VPS33A (Vacuolar Protein Sorting 33 Homolog A (VPS33A))
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别名
- VPS33A
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背景
- Synonyms:FLJ22395, FLJ23187, hVPS33A, VPS33A Background:Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes, the function is dependent on its association with VPS16 but not VIPAS39(PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG(PubMed:24554770).
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分子量
- 68 kDa
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基因ID
- 65082
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UniProt
- Q96AX1
抗原
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