UNC13A/Munc13-1 抗体
Quick Overview for UNC13A/Munc13-1 抗体 (ABIN7120613)
抗原
See all UNC13A/Munc13-1 (UNC13A) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- unc-13 homolog A(C. elegans)
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))
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别名
- UNC13A/Munc13-1
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背景
- Synonyms:KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A Background:UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.
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分子量
- 193 kDa
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途径
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
抗原
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