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UXT 抗体 (AA 1-157)

The 兔 多克隆 anti-UXT antibody is suitable to detect UXT in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7120577
发货至: 中国
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Quick Overview for UXT 抗体 (AA 1-157) (ABIN7120577)

抗原

See all UXT 抗体
UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

适用

  • 25
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 23
  • 2
  • 2

克隆类型

  • 27
多克隆

标记

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UXT antibody is un-conjugated

应用范围

  • 18
  • 8
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-157

    原理

    UXT antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-157aa

    Immunogen: ubiquitously-expressed transcript

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

    别名

    UXT

    背景

    Synonyms: Protein UXT|Androgen receptor trapped clone 27 protein (ART-27)|Ubiquitously expressed transcript protein|UXT

    Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription(AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation(PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling(PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC(PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function(PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM(PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.

    分子量

    18 kDa

    基因ID

    8409

    UniProt

    Q9UBK9

    途径

    Unfolded Protein Response
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