UXT 抗体 (AA 1-157)
Quick Overview for UXT 抗体 (AA 1-157) (ABIN7120577)
抗原
See all UXT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-157
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原理
- UXT antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-157aa
Immunogen: ubiquitously-expressed transcript
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))
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别名
- UXT
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背景
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Synonyms: Protein UXT|Androgen receptor trapped clone 27 protein (ART-27)|Ubiquitously expressed transcript protein|UXT
Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription(AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation(PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling(PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC(PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function(PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM(PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.
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分子量
- 18 kDa
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基因ID
- 8409
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UniProt
- Q9UBK9
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途径
- Unfolded Protein Response
抗原
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